Raul Rabadan, PhD, received his PhD in Theoretical Physics in 2001 and went on to conduct research in that field at the European Laboratory for Particle Physics (CERN) in Geneva, Switzerland, and at the Institute for Advanced Study (IAS) in Princeton. In 2006, he joined the Systems Biology program at IAS as a Martin A. and Helen Chooljian Member. In 2008, he joined the faculty at Columbia University, where he is a tenured Associate Professor with joint appointments in the Departments of Systems Biology and Biomedical Informatics. Dr. Rabadan is a member of the Scientific Advisory Board of the JP Sulzberger Columbia Genome Center. At Columbia University, Dr. Rabadan leads a highly interdisciplinary lab with researchers from the fields of mathematics, physics, computer science, engineering, and medicine, with the common goal of solving pressing biomedical problems through quantitative computational models. His work is mainly focused on developing tools to analyze genomic data, extracting the relevant information to understand the molecular biology, population genetics, evolution, and epidemiology of cancer.
Antonio Iavarone, MD, is a Professor of Pathology and Cell Biology, and Neurology at the Columbia University Medical Center’s Institute for Cancer Genetics. The overarching theme of his research program is the dissection of the role of proteins and networks that drive phenotypic states in normal and cancer cells from the nervous system. Using integrated systems biology and experimental pipelines tailored to the most significant and unbiased cancer modules, his research group has undertaken the task of identifying driver genes of aggressiveness in distinct sub-groups of GBM. His work has led to several landmark discoveries, including the transcriptional module for the mesenchymal subgroup of GBM, the first example of recurrent, oncogenic and addicting gene fusions in GBM, and the integrated landscape of driver alterations in GBM.